Pesquisa sobre: MYCOPHENOLIC ACID 
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Descritor Inglês:   Mycophenolic Acid 
Descritor Espanhol:   Ácido Micofenólico 
Descritor Português:   Ácido Micofenólico 
Sinônimos Inglês:   Cellcept
Mofetil Hydrochloride, Mycophenolate
Mofetil, Mycophenolate
Mycophenolate Mofetil
Mycophenolate Mofetil Hydrochloride
Mycophenolate Sodium
Mycophenolate, Sodium
Mycophenolic Acid Morpholinoethyl Ester
Myfortic
RS 61443
RS-61443
RS61443
Sodium Mycophenolate  
Categoria:   D02.241.081.193.678
D10.251.618
Definição Inglês:   Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION. 
Ação Farmacológica:   Antibiotics, Antineoplastic
Antibiotics, Antitubercular
Enzyme Inhibitors
 
Nota Histórica Inglês:   2017 (1999) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   9365 
Identificador Único:   D009173 

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