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Descriptor English: Naltrexone
Descriptor Spanish: Naltrexona
Descriptor naltrexona
Entry term(s) EN-1639A
Scope note: Derivado de la noroximorfona que es el congénere N-ciclopropilmetil de la NALOXONA. Es un antagonista narcótico eficaz por vía oral, de acción más prolongada y más potente que la naloxona, y que se ha propuesto para el tratamiento de la adicción a la heroína. La FDA ha aprobado la naltrexona para el tratamiento de la dependencia al alcohol.
Descriptor Portuguese: Naltrexona
Descriptor French: Naltrexone
Entry term(s): Antaxone
Celupan
EN 1639A
EN-1639A
EN1639A
Nalorex
Naltrexone Hydrochloride
Nemexin
ReVia
Trexan
Tree number(s): D03.132.577.249.706.550
D03.605.497.750.550
D03.633.400.686.750.550
D04.615.723.795.706.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009271
Scope note: Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Alcohol Deterrents
Narcotic Antagonists
Registry Number: 5S6W795CQM
CAS Type 1 Name: Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
Previous Indexing: Cyclopropanes (1973-1975)
Morphinans (1973-1974)
Naloxone/analogs & derivatives (1975)
Public MeSH Note: 1986; NALTREXONE was indexed under NALOXONE 1976-1985
History Note: 1986 (1976)
DeCS ID: 9463
Unique ID: D009271
NLM Classification: QV 89
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1975/07/23
Revision Date: 2018/04/10
Naltrexone - Preferred
Concept UI M0014445
Scope note Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Preferred term Naltrexone
Antaxone - Narrower
Concept UI M0462923
Preferred term Antaxone
Trexan - Narrower
Concept UI M0352956
Preferred term Trexan
EN-1639A - Narrower
Concept UI M0014444
Preferred term EN-1639A
Entry term(s) EN 1639A
EN1639A
ReVia - Narrower
Concept UI M0462925
Preferred term ReVia
Entry term(s) Nalorex
Nemexin
Naltrexone Hydrochloride - Narrower
Concept UI M0462922
Preferred term Naltrexone Hydrochloride
Celupan - Narrower
Concept UI M0462924
Preferred term Celupan



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