Pesquisa sobre: NEOPLASM PROTEINS 
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Descritor Inglês:   Neoplasm Proteins 
Descritor Espanhol:   Proteínas de Neoplasias 
Descritor Português:   Proteínas de Neoplasias 
Sinônimos Inglês:   Proteins, Neoplasm  
Categoria:   D12.776.624
Definição Inglês:   Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm. 
Nota de Indexação Inglês:   IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual
Relacionados Inglês:   Antigens, Neoplasm
Biomarkers, Tumor
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   9556 
Identificador Único:   D009363 

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