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Descriptor English: Nigericin
Descriptor Spanish: Nigericina
Descriptor nigericina
Entry term(s) nigericín
Scope note: Antibiótico poliéter que afecta el transporte iónico y la actividad de ATPasa en la mitocondria. Lo produce el Streptomyces hygroscopicus.
Descriptor Portuguese: Nigericina
Descriptor French: Nigéricine
Entry term(s): Epinigericin
Pandavir
Tree number(s): D03.383.312.634
D03.383.663.620
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009550
Scope note: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Ionophores
Registry Number: RRU6GY95IS
CAS Type 1 Name: Nigericin
Previous Indexing: Antibiotics (1969-1974)
Carboxylic Acids (1973-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS 1975-90
History Note: 91(75); was see under ANTIBIOTICS 1975-90
DeCS ID: 9736
Unique ID: D009550
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Nigericin - Preferred
Concept UI M0014855
Scope note A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Preferred term Nigericin
Pandavir - Narrower
Concept UI M0353184
Preferred term Pandavir
Epinigericin - Related but not broader or narrower
Concept UI M0014856
Preferred term Epinigericin



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