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Descritor Inglês:   Nitrogen Mustard Compounds 
Descritor Espanhol:   Compuestos de Mostaza Nitrogenada 
Descritor Português:   Compostos de Mostarda Nitrogenada 
Sinônimos Inglês:   Compounds, Nitrogen Mustard
Mustard Compounds, Nitrogen  
Categoria:   D02.455.526.728.650
Definição Inglês:   A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens. 
Nota de Indexação Inglês:   do not confuse with NITROGEN MUSTARD, a specific chemical
Ação Farmacológica:   Antineoplastic Agents, Alkylating
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número do Registro:   9773 
Identificador Único:   D009588 

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