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Descriptor English: Ondansetron
Descriptor Spanish: Ondansetrón
Descriptor ondansetrón
Entry term(s) 1,2,3,9-tetrahidro-9-metil-3-((2-metil-1H-imidazol-1-il)metil)-4H-carbazol-4-ona
Zofran ODT
Scope note: Antagonista competitivo de los receptores tipo 3 de serotonina. Es eficaz en el tratamiento de las náuseas y el vómitos ocasionados por fármacos quimioterápicas citotóxicas, incluido el cisplatino, y se le atribuyen propiedades ansiolíticas y neurolépticas.
Descriptor Portuguese: Ondansetron
Descriptor French: Ondansétron
Entry term(s): 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-
Dihydrate, Ondansetron Monohydrochloride
GR 38032F
GR-38032F
GR38032F
Hydrochloride, Ondansetron
Monohydrochloride Dihydrate, Ondansetron
Monohydrochloride, Ondansetron
ODT, Zofran
Ondansetron Hydrochloride
Ondansetron Monohydrochloride
Ondansetron Monohydrochloride Dihydrate
Ondansetron, (+,-)-Isomer
Ondansetron, (R)-Isomer
Ondansetron, (S)-Isomer
SN 307
SN-307
SN307
Zofran
Zofran ODT
Tree number(s): D03.383.129.308.690
D03.633.100.473.144.500
D03.633.300.148.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017294
Scope note: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiemetics
Antipruritics
Serotonin Antagonists
Antipsychotic Agents
Anti-Anxiety Agents
Registry Number: 4AF302ESOS
CAS Type 1 Name: 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-
Previous Indexing: Imidazoles (1987-1992)
Public MeSH Note: 93; ONDANSETRON was indexed under IMIDAZOLES 1987-92
Online Note: use ONDANSETRON (NM) to search ONDANSETRON 1987-92
History Note: 93; was ONDANSETRON (NM) 1987-92
DeCS ID: 30632
Unique ID: D017294
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/19
Revision Date: 2022/07/14
Ondansetron - Preferred
Concept UI M0026254
Scope note A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Preferred term Ondansetron
Entry term(s) 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-
Ondansetron, (+,-)-Isomer
Ondansetron, (R)-Isomer - Narrower
Concept UI M0329264
Preferred term Ondansetron, (R)-Isomer
Ondansetron, (S)-Isomer - Narrower
Concept UI M0329263
Preferred term Ondansetron, (S)-Isomer
GR38032F - Narrower
Concept UI M0026255
Preferred term GR38032F
Entry term(s) GR 38032F
GR-38032F
Zofran - Narrower
Concept UI M0353338
Preferred term Zofran
Ondansetron Hydrochloride - Narrower
Concept UI M0329262
Preferred term Ondansetron Hydrochloride
Entry term(s) Dihydrate, Ondansetron Monohydrochloride
Hydrochloride, Ondansetron
Monohydrochloride Dihydrate, Ondansetron
Monohydrochloride, Ondansetron
Ondansetron Monohydrochloride
Ondansetron Monohydrochloride Dihydrate
SN-307 - Narrower
Concept UI M0353339
Preferred term SN-307
Entry term(s) SN 307
SN307
Zofran ODT - Narrower
Concept UI M000754320
Preferred term Zofran ODT
Entry term(s) ODT, Zofran



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