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Descriptor English: Plectin
Descriptor Spanish: Plectina
Descriptor plectina
Scope note: Proteína de unión al citoesqueleto cuyo peso molecular supera los 500 kDa. Se une a los FILAMENTOS INTERMEDIOS, MICROTÚBULOS y CITOESQUELETO DE ACTINA y desempeña un papel fundamental en la organización y estabilidad del CITOESQUELETO. La plectina es fosforilada por la CALMODULINA-CINASA, la PROTEINCINASA A y la PROTEINCINASA C.
Descriptor Portuguese: Plectina
Descriptor French: Plectine
Entry term(s): 500 kDa HD1 Protein
500-kDa HD1 Protein
HD1 Protein, 500-kDa
HD1, Hemidesmosomal Protein
Hemidesmosomal Protein HD1
Tree number(s): D12.776.220.790.750
D12.776.744.736
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051190
Scope note: A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; PLECTIN was indexed under INTERMEDIATE FILAMENT PROTEINS 1992-2005, & under PROTEINS 1982-1991
History Note: 2006(1982)
DeCS ID: 50941
Unique ID: D051190
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2011/07/01
Plectin - Preferred
Concept UI M0105731
Scope note A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.
Preferred term Plectin
Entry term(s) 500 kDa HD1 Protein
500-kDa HD1 Protein
HD1 Protein, 500-kDa
HD1, Hemidesmosomal Protein
Hemidesmosomal Protein HD1



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