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Descriptor English: Polymyxins
Descriptor Spanish: Polimixinas
Descriptor polimixinas
Entry term(s) polimixina
Scope note: Grupo de antibióticos lipopeptídicos básicos obtenidos del Bacillus polymyxa. Afectan la membrana celular por su acción detergente y pueden causar daño neuromuscular y renal. Se han identificado, como mínimo, once miembros diferentes del grupo de las polimixinas, cada uno designado por una letra.
Descriptor Portuguese: Polimixinas
Descriptor French: Polymyxines
Entry term(s): Polymyxin
Polymyxin M
Tree number(s): D04.345.566.780
D10.477.750
D12.644.050.600
D12.644.066.500.600
D12.644.641.780
D12.776.543.695.054.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011113
Scope note: Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Public MeSH Note: 1994,1963-1977; see POLYMYXIN 1994-2003; see POLYMYXINS 1978-93; see POLYMYXIN 1963-77
History Note: 1994,1963-1977
DeCS ID: 31775
Unique ID: D011113
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1999/01/01
Revision Date: 2008/07/08
Polymyxins - Preferred
Concept UI M0017217
Scope note Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
Preferred term Polymyxins
Entry term(s) Polymyxin
Polymyxin M - Narrower
Concept UI M0017216
Preferred term Polymyxin M



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