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Descritor Inglês:   Proto-Oncogene Proteins c-abl 
Descritor Espanhol:   Proteínas Proto-Oncogénicas c-abl 
Descritor Português:   Proteínas Proto-Oncogênicas c-abl 
Sinônimos Inglês:   Products, abl Proto-Oncogene
Proteins abl, Proto-Oncogene
Proto Oncogene Proteins abl
Proto Oncogene Proteins c abl
Proto-Oncogene Products, abl
Proto-Oncogene Proteins abl
Proto-Oncogene Proteins, abl
abl Proto Oncogene Products
abl Proto Oncogene Proteins
abl Proto-Oncogene Products
abl Proto-Oncogene Proteins
abl, Proto-Oncogene Proteins
c abl Proteins
c-abl Proteins
c-abl, Proto-Oncogene Proteins  
Categoria:   D08.811.913.696.620.682.725.500
Definição Inglês:   Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation. 
Relacionados Inglês:   Fusion Proteins, bcr-abl
Nota Histórica Inglês:   91 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   29092 
Identificador Único:   D016315 

Ocorrência na BVS: