Pesquisa sobre: RNA-BINDING PROTEIN FUS 
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Descritor Inglês:   RNA-Binding Protein FUS 
Descritor Espanhol:   Proteína FUS de Unión a ARN 
Descritor Português:   Proteína FUS de Ligação a RNA 
Sinônimos Inglês:   FUS Protein
FUS RNA Binding Protein
FUS RNA-Binding Protein
Fusion Protein in Myxoid Liposarcoma
POMp75 Protein
RNA Binding Protein FUS
RNA-Binding Protein, FUS
TLS Protein
Translocated in Liposarcoma Protein
hnRNP P2  
Categoria:   D12.776.157.725.813.750.905
D12.776.624.664.700.915
D12.776.664.962.813.750.902
Definição Inglês:   A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia. 
Nota Histórica Inglês:   2003; for FUS PROTEIN & HNRNP P2 use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1996-2002; for TLS PROTEIN use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1993-2002; 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   37420 
Identificador Único:   D034702 

Ocorrência na BVS:
 
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