Pesquisa sobre: RECEPTORS, LDL 
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Descritor Inglês:   Receptors, LDL 
Descritor Espanhol:   Receptores de LDL 
Descritor Português:   Receptores de LDL 
Sinônimos Inglês:   LDL Receptor
LDL Receptors
LDL Receptors, Lipoprotein
Lipoprotein LDL Receptors
Low Density Lipoprotein Receptor
Low Density Lipoprotein Receptors
Receptor, LDL
Receptors, Lipoprotein LDL
Receptors, Lipoprotein, LDL
Receptors, Low Density Lipoprotein  
Categoria:   D12.776.543.750.710.450
Definição Inglês:   Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking. 
Relacionados Inglês:   Lipoproteins, LDL
 
Nota Histórica Inglês:   85; LIPOPROTEINS, LDL RECEPTORS was see RECEPTORS, LDL 1985-92 
Qualificadores Permitidos Inglês:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Número do Registro:   22650 
Identificador Único:   D011973 

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