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Descritor Inglês:   Receptors, Leukocyte-Adhesion 
Descritor Espanhol:   Receptores de Adhesión de Leucocito 
Descritor Português:   Receptores de Adesão de Leucócito 
Sinônimos Inglês:   Family, Leu-CAM Receptor
Leu CAM Receptor Family
Leu-CAM Receptor Family
Leukocyte Adhesion Receptor
Leukocyte Adhesion Receptor Family
Leukocyte Adhesion Receptors
Leukocyte-Adhesion Receptor
Leukocyte-Adhesion Receptor Family
Leukocyte-Adhesion Receptors
Receptor Family, Leu-CAM
Receptor, Leukocyte-Adhesion
Receptors, Leukocyte Adhesion  
Categoria:   D12.776.543.750.705.408.600
Definição Inglês:   Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells. 
Relacionados Inglês:   Leukocyte-Adhesion Deficiency Syndrome
Nota Histórica Inglês:   90 
Qualificadores Permitidos Inglês:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DE drug effects GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PH physiology RE radiation effects
TU therapeutic use UL ultrastructure
Número do Registro:   24855 
Identificador Único:   D016028 

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