Pesquisa sobre: SRS-A 
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Descritor Inglês:   SRS-A 
Descritor Espanhol:   SRS-A 
Descritor Português:   SRS-A 
Sinônimos Inglês:   Slow Reacting Substance of Anaphylaxis  
Categoria:   D10.251.355.255.100.450.855
Definição Inglês:   A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed) 
Nota de Indexação Inglês:   /biosyn /physiol permitted
Nota Histórica Inglês:   73(67) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   24317 
Identificador Único:   D013189 

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