Search
Descriptor English: Trichosanthin
Descriptor Spanish: Tricosantina
Descriptor tricosantina
Entry term(s) compuesto Q
tricosantina alfa
Scope note: Proteína purificada que inactiva a los ribosomas derivados de plantas medicinales Chinas del grupo tian-huan-fen que se obtiene de las raíces tuberosas de la Trichosanthes kirilowii. Se ha utilizado como abortivo y en el tratamiento de los tumores trofoblásticos. El GLQ223 (Compuesto Q), forma altamente purificada de tricosantina, se ha propuesto como tratamiento antiviral para el SIDA.
Descriptor Portuguese: Tricosantina
Descriptor French: Trichosanthine
Entry term(s): Compound Q
GLQ 223
GLQ-223
GLQ223
T'ien-hua-fen
Tian-hua-fen
alpha Trichosanthin
alpha-Trichosanthin
Tree number(s): D12.776.765.710.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015978
Scope note: Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
Annotation: /drug eff /ultrastruct permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Abortifacient Agents, Nonsteroidal
Antineoplastic Agents, Phytogenic
Anti-HIV Agents
Registry Number: 60318-52-7
CAS Type 1 Name: Proteins, specific or class, trichosanthins
Previous Indexing: Abortifacient Agents, Non-Steroidal (1977-1989)
Plant Proteins (1976-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24902
Unique ID: D015978
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2007/07/09
Trichosanthin - Preferred
Concept UI M0024413
Scope note Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
Preferred term Trichosanthin
Entry term(s) Compound Q
alpha Trichosanthin
alpha-Trichosanthin
Tian-hua-fen - Related but not broader or narrower
Concept UI M0391328
Preferred term Tian-hua-fen
Entry term(s) T'ien-hua-fen
GLQ-223 - Narrower
Concept UI M0373906
Preferred term GLQ-223
Entry term(s) GLQ 223
GLQ223



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey