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Descriptor English: Virosomes
Descriptor Spanish: Virosomas
Descriptor virosomas
Scope note: Complejo semisintético derivado de partículas víricas carentes de ácido nucleico. Esencialmente son cubiertas víricas reconstituidas en las que el nucleocápside infeccioso es sustituido por el compuesto elegido. Los virosomas conservan su actividad fusógena y de ese modo liberan el compuesto incorporado (antígenos, fármacos, genes) en el interior de la célula en la que actúan. Pueden utilizarse en vacunas (VACUNAS DE VIROSOMAS), en la administración de fármacos o la transferencia de genes.
Descriptor Portuguese: Virossomos
Descriptor French: Virosomes
Entry term(s): Virosome
Tree number(s): D25.479.900
D26.255.260.900
J01.637.051.479.900
J01.637.087.500.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D022701
Scope note: Semi-synthetic complex derived from nucleic-acid free viral particles. They are essentially reconstituted viral coats, where the infectious nucleocapsid is replaced by a compound of choice. Virosomes retain their fusogenic activity and thus deliver the incorporated compound (antigens, drugs, genes) inside the target cell. They can be used for vaccines (VACCINES, VIROSOME), drug delivery, or gene transfer.
Annotation: when used as a vehicle in drug ther, index specific drug /admin (IM) + VIROSOMES (NIM without qualif)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Liposomes (1975-2000)
Public MeSH Note: 2001
History Note: 2001
Related: Vaccines, Virosome MeSH
DeCS ID: 35389
Unique ID: D022701
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2001/01/01
Date of Entry: 2000/06/22
Revision Date: 2006/07/05
Virosomes - Preferred
Concept UI M0358923
Scope note Semi-synthetic complex derived from nucleic-acid free viral particles. They are essentially reconstituted viral coats, where the infectious nucleocapsid is replaced by a compound of choice. Virosomes retain their fusogenic activity and thus deliver the incorporated compound (antigens, drugs, genes) inside the target cell. They can be used for vaccines (VACCINES, VIROSOME), drug delivery, or gene transfer.
Preferred term Virosomes
Entry term(s) Virosome



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