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Descriptor English: Elafin
Descriptor Spanish: Elafina
Descriptor elafina
Scope note: Proteína inhibidora de proteinasa secretora que fue purificada inicialmente a partir de la PIEL humana. Se encuentra en una variedad de secreciones mucosas y se halla presenta en grandes concentraciones en el ESPUTO. La elafina puede desempeñar un papel en la respuesta inmunitaria innata (INMUNIDAD INNATA) del PULMÓN.
Descriptor Portuguese: Elafina
Descriptor French: Élafine
Entry term(s): Antileukoproteinase, Skin-Derived
Inhibitor WAP3, Protease
Peptidase Inhibitor 3, Skin derived
Peptidase Inhibitor 3, Skin-derived
Protease Inhibitor 3, Skin derived
Protease Inhibitor 3, Skin-derived
Protease Inhibitor WAP3
Skin Derived Antileukoproteinase
Skin-Derived Antileukoproteinase
Tree number(s): D12.644.822.437
D12.776.815.437
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053492
Scope note: A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Protease Inhibitors
Previous Indexing: Protease Inhibitors (1990-2006)
Public MeSH Note: 2007; ELAFIN was indexed under PROTEINS 2005-2006
History Note: 2007(2005)
DeCS ID: 52318
Unique ID: D053492
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Elafin - Preferred
Concept UI M0485533
Scope note A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.
Preferred term Elafin
Entry term(s) Antileukoproteinase, Skin-Derived
Inhibitor WAP3, Protease
Peptidase Inhibitor 3, Skin derived
Peptidase Inhibitor 3, Skin-derived
Protease Inhibitor 3, Skin derived
Protease Inhibitor 3, Skin-derived
Protease Inhibitor WAP3
Skin Derived Antileukoproteinase
Skin-Derived Antileukoproteinase



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