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Descriptor English: Adenylosuccinate Lyase
Descriptor Spanish: Adenilosuccinato Liasa
Descriptor adenilosuccinato cinasa
Entry term(s) adenilosuccinasa
Scope note: Enzima que, durante la biosíntesis de ribonucleótidos purínicas, cataliza la conversión de 5'-fosforribosil-4-(N-succinocarboxamida)-5-aminoimidazol en 5'-fosforribosil-4-carboxamida-5-aminoimidazol y la conversión de ácido adenilosuccínico en AMP. EC 4.3.2.2.
Descriptor Portuguese: Adenilossuccinato Liase
Descriptor French: Adenylosuccinate lyase
Entry term(s): Adenylosuccinase
Lyase, Adenylosuccinate
Tree number(s): D08.811.520.232.300.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000264
Scope note: An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.3.2.2
CAS Type 1 Name: N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase
Previous Indexing: Adenosine Monophosphate (1971-1978)
Lyases (1966-1978)
Succinates (1966-1978)
Public MeSH Note: 91; was see under LYASES 1979-90
History Note: 91(79); was see under LYASES 1979-90
DeCS ID: 271
Unique ID: D000264
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1978/05/16
Revision Date: 2003/07/09
Adenylosuccinate Lyase - Preferred
Concept UI M0000414
Scope note An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.
Preferred term Adenylosuccinate Lyase
Entry term(s) Adenylosuccinase
Lyase, Adenylosuccinate



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