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Descriptor English: Adrenomedullin
Descriptor Spanish: Adrenomedulina
Descriptor adrenomedulina
Scope note: Péptido de 52 aminoácidos con funciones múltiples. Inicialmente se aisló en el FEOCROMOCITOMA y la MÉDULA SUPRARRENAL pero está ampliamente distribuido en todo el organismo, incluidos los tejidos pulmonar y renal. Además de controlar la homeostasis hidroelectrolítica, es un potente vasodilatador y puede inhibir la secreción hipofisaria de ACTH.
Descriptor Portuguese: Adrenomedulina
Descriptor French: Adrénomédulline
Entry term(s): ADM (1-52)
ADM(1-52)
Adrenomedullin (1-52)
PAMP(1-20)NH2
Proadrenomedullin (1-20)
Proadrenomedullin N Terminal 20 Peptide
Proadrenomedullin N-Terminal 20 Peptide
Tree number(s): D06.472.699.077
D12.644.548.017
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053607
Scope note: A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Bronchodilator Agents
Cardiotonic Agents
Vasodilator Agents
Registry Number: 148498-78-6
Previous Indexing: Peptides (1993-2006)
Public MeSH Note: 2007; ADRENOMEDULLIN was indexed under PEPTIDES 1993-2006
History Note: 2007 (1993)
DeCS ID: 52207
Unique ID: D053607
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Adrenomedullin - Preferred
Concept UI M0216201
Scope note A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.
Preferred term Adrenomedullin
Entry term(s) ADM (1-52)
ADM(1-52)
Adrenomedullin (1-52)
PAMP(1-20)NH2 - Related but not broader or narrower
Concept UI M0459452
Preferred term PAMP(1-20)NH2
Entry term(s) Proadrenomedullin (1-20)
Proadrenomedullin N Terminal 20 Peptide
Proadrenomedullin N-Terminal 20 Peptide



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