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Descriptor English: Ancrod
Descriptor Spanish: Ancrod
Descriptor ancrod
Entry term(s) proteasa del veneno de Agkistrodon rhodostoma
serina-proteinasa de Agkistrodon
Scope note: Fracción enzimática del veneno de la víbora de Malasia, Agkistrodon rhodostoma. Cataliza la hidrólisis de un grupo ésteres de ciertos aminoácidos y una proteólisis limitada del fibrinógeno. Se emplea clínicamente para producir la desfibrinación controlada en pacientes que requieren terapia anticoagulante. EC 3.4.21.-.
Descriptor Portuguese: Ancrod
Descriptor French: Ancrod
Entry term(s): Agkistrodon Serine Proteinase
Agkistrodon rhodostoma Venom Protease
Arvin
Arvin IRC 50
Arvin IRC-50
Arvin IRC50
Arwin
Venacil
Tree number(s): D08.811.277.656.300.760.955.060
D08.811.277.656.959.350.955.060
D20.888.850.960.200.050
D23.946.833.850.960.200.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000721
Scope note: An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Anticoagulants
Fibrinolytic Agents
Registry Number: EC 3.4.21.-
Previous Indexing: Peptide Hydrolases (1972-1974)
Peptide Peptidohydrolases (1966-1974)
Venoms (1972-1974)
Public MeSH Note: 78; was ARVIN see under PEPTIDE PEPTIDOHYDROLASES 1975-77; ARVIN was see ANCROD 1978-95
Online Note: use ANCROD to search ARVIN 1975-77
History Note: 78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
DeCS ID: 23155
Unique ID: D000721
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/07/05
Ancrod - Preferred
Concept UI M0001092
Scope note An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
Preferred term Ancrod
Entry term(s) Agkistrodon Serine Proteinase
Agkistrodon rhodostoma Venom Protease
Arvin IRC-50 - Narrower
Concept UI M0001093
Preferred term Arvin IRC-50
Entry term(s) Arvin IRC 50
Arvin IRC50
Venacil - Narrower
Concept UI M0332983
Preferred term Venacil
Arvin - Narrower
Concept UI M0001094
Preferred term Arvin
Entry term(s) Arwin



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