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Descriptor English: Thiram
Descriptor Spanish: Tiram
Descriptor tiram
Scope note: Ditiocarbamato que se utiliza comercialmente en la industria del procesado del caucho y como fungicida. Los estudios in vivo indican que este compuesto inactiva la enzima GLUTATIÓN REDUCTASA. Tiene actividad mutagénica y puede inducir aberraciones cromosómicas.
Descriptor Portuguese: Tiram
Descriptor French: Thirame
Entry term(s): Bacteriostat
Disulfide, TMT
Disulfide, Tetramethylthiuram
Nobecutan
Sadoplon 75
TMT Disulfide
TMTD
Tetramethylthiuram Disulfide
Thiuram
Thiuram D
Tree number(s): D02.241.081.251.869.210.800
D02.886.706.175.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013893
Scope note: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Fungicides, Industrial
Mutagens
Registry Number: 0D771IS0FH
CAS Type 1 Name: Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-
Public MeSH Note: 91; was see under THIOCARBAMATES 1966-90
History Note: 91(66); was see under THIOCARBAMATES 1966-90
DeCS ID: 14279
Unique ID: D013893
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Thiram - Preferred
Concept UI M0021389
Scope note A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
Preferred term Thiram
Entry term(s) Disulfide, TMT
Disulfide, Tetramethylthiuram
TMT Disulfide
TMTD
Tetramethylthiuram Disulfide
Thiuram
Nobecutan - Narrower
Concept UI M0021390
Preferred term Nobecutan
Thiuram D - Narrower
Concept UI M0351503
Preferred term Thiuram D
Bacteriostat - Narrower
Concept UI M0551818
Preferred term Bacteriostat
Sadoplon 75 - Narrower
Concept UI M0351504
Preferred term Sadoplon 75



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