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Descriptor English: Cladribine
Descriptor Spanish: Cladribina
Descriptor cladribina
Entry term(s) 2-cloro-2'-desoxiadenosina
2-clorodesoxiadenosina
Scope note: Agente antineoplásico utilizado en el tratamiento de las enfermedades linfoproliferativas, incluida la leucemia de células pilosas.
Descriptor Portuguese: Cladribina
Descriptor French: Chloro-2 désoxyadénosine
Entry term(s): 2'-Deoxy-2-chloroadenosine
2-Chloro-2'-deoxyadenosine
2-Chlorodeoxyadenosine
Leustatin
Tree number(s): D03.633.100.759.590.138.300.200
D03.633.100.759.590.138.325.075
D13.570.230.229.075
D13.570.583.138.300.200
D13.570.583.138.325.075
D13.570.800.096.300.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017338
Scope note: An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Immunosuppressive Agents
Registry Number: 47M74X9YT5
CAS Type 1 Name: Adenosine, 2-chloro-2'-deoxy-
Previous Indexing: 2-Chloroadenosine/analogs & derivatives (1986-1992)
Deoxyadenosines (1986-1992)
Public MeSH Note: 95; was 2-CHLORODEOXYADENOSINE 1993-94; 2-CHLORO-2'-DEOXYADENOSINE was indexed under 2-CHLOROADENOSINE/analogs & derivatives & DEOXYADENOSINES 1986-92
Online Note: use CLADRIBINE to search 2-CHLORODEOXYADENOSINE 1993-94; use CLADRIBINE (NM) to search 2-CHLORO-2'-DEOXYADENOSINE 1986-92
History Note: 95; was 2-CHLORODEOXYADENOSINE 1993-94; was 2-CHLORO-2'-DEOXYADENOSINE (NM) 1986-92
DeCS ID: 30454
Unique ID: D017338
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2016/05/28
Cladribine - Preferred
Concept UI M0026332
Scope note An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
Preferred term Cladribine
Entry term(s) 2'-Deoxy-2-chloroadenosine
2-Chloro-2'-deoxyadenosine
2-Chlorodeoxyadenosine
Leustatin - Narrower
Concept UI M0373300
Preferred term Leustatin



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