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Descriptor English: Danazol
Descriptor Spanish: Danazol
Descriptor danazol
Scope note: Esteroide sintético con actividad antigonadotrópica y antiestrogénica, que actúa como supresor en la adenohipófisis inhibiendo la salida de las gonadotropinas de la hipófisis. Posee algunas propiedades androgénicas. El danazol se ha utilizado en el tratamiento de la endometriosis y de algunos trastornos mamarios benignos.
Descriptor Portuguese: Danazol
Descriptor French: Danazol
Entry term(s): Azol
Cyclomen
Danatrol
Danazant
Danazol Ratiopharm
Danazol-Ratiopharm
Danocrine
Danol
Danoval
Ladogal
Norciden
Panacrine
Tree number(s): D04.210.500.745.432.235
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003613
Scope note: A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Estrogen Antagonists
Registry Number: N29QWW3BUO
CAS Type 1 Name: Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)-
Previous Indexing: Alkynes (1973-1974)
Hydroxysteroids (1973-1974)
Oxazoles (1973-1974)
Pregnadienes (1973-1974)
Public MeSH Note: 91; was see under PREGNADIENES 1975-90
History Note: 91(75); was see under PREGNADIENES 1975-90
DeCS ID: 3632
Unique ID: D003613
NLM Classification: WP 522
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2017/05/24
Danazol - Preferred
Concept UI M0005648
Scope note A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Preferred term Danazol
Danazant - Narrower
Concept UI M0485003
Preferred term Danazant
Panacrine - Related but not broader or narrower
Concept UI M0005649
Preferred term Panacrine
Danocrine - Narrower
Concept UI M0361541
Preferred term Danocrine
Entry term(s) Cyclomen
Danatrol
Danol
Ladogal
Danoval - Narrower
Concept UI M0351295
Preferred term Danoval
Norciden - Narrower
Concept UI M0485001
Preferred term Norciden
Azol - Narrower
Concept UI M0485004
Preferred term Azol
Danazol-Ratiopharm - Narrower
Concept UI M0485002
Preferred term Danazol-Ratiopharm
Entry term(s) Danazol Ratiopharm



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