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Descriptor English: Dextropropoxyphene
Descriptor Spanish: Dextropropoxifeno
Descriptor dextropropoxifeno
Entry term(s) D-propoxifeno
Scope note: Analgésico narcótico relacionado estructuralmente con la METADONA. Sólo el isómero dextro tiene efecto analgésico; parece que el isómero levo ejerce un efecto antitusivo.
Descriptor Portuguese: Dextropropoxifeno
Descriptor French: Dextropropoxyphène
Entry term(s): D Propoxyphene
D-Propoxyphene
Darvon
Hydrochloride, Propoxyphene
Propoxyphene
Propoxyphene Hydrochloride
Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer
Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer
Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer
Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer
Propoxyphene Maleate, (+)-Isomer
Propoxyphene Phosphate, (S-(R*,S*))-Isomer
Propoxyphene Sulfate, (S-(R*,S*))-Isomer
Tree number(s): D02.241.081.751.120
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011431
Scope note: A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics, Opioid
Narcotics
Registry Number: S2F83W92TK
CAS Type 1 Name: Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (S-(R*,S*))-
Public MeSH Note: 1965; see PROPOXYPHENE 1965-2008; DEXTRO PROPOXYPHENE was heading 1963-64
History Note: 2008(1965); DEXTRO PROPOXYPHENE was heading 1963-1964
DeCS ID: 11863
Unique ID: D011431
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Dextropropoxyphene - Preferred
Concept UI M0017770
Scope note A narcotic analgesic structurally related to METHADONE. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect.
Preferred term Dextropropoxyphene
Entry term(s) D Propoxyphene
D-Propoxyphene
Propoxyphene
Propoxyphene Hydrochloride - Narrower
Concept UI M0353504
Preferred term Propoxyphene Hydrochloride
Entry term(s) Hydrochloride, Propoxyphene
Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer - Narrower
Concept UI M0329778
Preferred term Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer
Propoxyphene Sulfate, (S-(R*,S*))-Isomer - Narrower
Concept UI M0329771
Preferred term Propoxyphene Sulfate, (S-(R*,S*))-Isomer
Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer - Narrower
Concept UI M0329773
Preferred term Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer
Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer - Narrower
Concept UI M0329780
Preferred term Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer
Propoxyphene Maleate, (+)-Isomer - Narrower
Concept UI M0329775
Preferred term Propoxyphene Maleate, (+)-Isomer
Propoxyphene Phosphate, (S-(R*,S*))-Isomer - Narrower
Concept UI M0329772
Preferred term Propoxyphene Phosphate, (S-(R*,S*))-Isomer
Darvon - Narrower
Concept UI M0017771
Preferred term Darvon
Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer - Narrower
Concept UI M0329781
Preferred term Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer



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