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Descriptor English: Toyocamycin
Descriptor Spanish: Toyocamicina
Descriptor toyocamicina
Entry term(s) desazacianoadenosina
Scope note: 4-amino-5-ciano-7-(D-ribofuranosil)-7H-pirrolo(2,3-d)pirimidina. Antibiótico antimetabolito aislado a partir de cultivos de Streptomyces toyocaensis. Es un análogo de la adenosina, bloquea la síntesis de ARN y la función de los ribosomas, y se utiliza principalmente en bioquímica.
Descriptor Portuguese: Toiocamicina
Descriptor French: Toyocamycine
Entry term(s): Deazacyanoadenosine
Toyokamycin
Tree number(s): D13.570.800.840
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014127
Scope note: 4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Annotation: an antineoplastic antibiotic & antimetabolite
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Antimetabolites, Antineoplastic
Registry Number: L7995C4D7F
CAS Type 1 Name: 7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-beta-D-ribofuranosyl-
Previous Indexing: Nitriles (1966-1974)
Nucleosides (1966-1972)
Pyrimidine Nucleosides (1974)
Pyrroles (1966-1974)
Ribonucleosides (1973-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, AMINOGLYCOSIDE 1981-90; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-80
History Note: 91(75); was see under ANTIBIOTICS, AMINOGLYCOSIDE 1981-90; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-80
DeCS ID: 23488
Unique ID: D014127
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Toyocamycin - Preferred
Concept UI M0021736
Scope note 4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
Preferred term Toyocamycin
Entry term(s) Deazacyanoadenosine
Toyokamycin



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