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Descriptor English: Dermcidins
Descriptor Spanish: Dermcidinas
Descriptor dermcidinas
Scope note: Péptidos con 47 aminoácidos segregados por las GLÁNDULAS ECRINAS y que intervienen en la defensa cutánea innata merced a su actividad antimicrobiana frente a determinadas BACTERIAS patógenas. Están sobreexpresadas en algunas células del CÁNCER DE MAMA primario. Derivan de PRECURSORES DE PROTEÍNAS con 110 residuos.
Descriptor Portuguese: Dermocidinas
Descriptor French: Dermcidines
Tree number(s): D12.644.050.400
D12.644.066.500.400
D12.776.543.695.054.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054805
Scope note: 47-amino acid peptides secreted by ECCRINE GLANDS and having a role in innate cutaneous defense, being antimicrobial to some pathogenic BACTERIA. They are overexpressed by some primary BREAST CANCER cells. They are derived from 110 residue PROTEIN PRECURSORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52754
Unique ID: D054805
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Dermcidins - Preferred
Concept UI M0507779
Scope note 47-amino acid peptides secreted by ECCRINE GLANDS and having a role in innate cutaneous defense, being antimicrobial to some pathogenic BACTERIA. They are overexpressed by some primary BREAST CANCER cells. They are derived from 110 residue PROTEIN PRECURSORS.
Preferred term Dermcidins



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