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Descriptor English: Dutasteride
Descriptor Spanish: Dutasterida
Descriptor dutasterida
Scope note: INHIBIDOR DE LA 5-ALFA-REDUCTASA que se presenta para inhibir las isoformas tanto de tipo 1 como de tipo2 de la enzima y es utilizado para tratar la HIPERPLASIA PROSTÁTICA BENIGNA.
Descriptor Portuguese: Dutasterida
Descriptor French: Dutastéride
Entry term(s): 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one
745, GG
Avodart
GG 745
GG-745
GG745
GI198745
Tree number(s): D04.210.500.925.100.125
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068538
Scope note: A 5-ALPHA-REDUCTASE INHIBITOR that is reported to inhibit both type-1 and type2 isoforms of the enzyme and is used to treat BENIGN PROSTATIC HYPERPLASIA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: 5-alpha Reductase Inhibitors
Registry Number: O0J6XJN02I
Public MeSH Note: 2016; DUTASTERIDE was indexed under AZASTEROIDS 1998-2015.
History Note: 2016 (1998)
DeCS ID: 55943
Unique ID: D000068538
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/31
Dutasteride - Preferred
Concept UI M0281571
Scope note A 5-ALPHA-REDUCTASE INHIBITOR that is reported to inhibit both type-1 and type2 isoforms of the enzyme and is used to treat BENIGN PROSTATIC HYPERPLASIA.
Preferred term Dutasteride
Entry term(s) 17beta-N-(2,5-bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one
Avodart - Narrower
Concept UI M0477724
Preferred term Avodart
GG 745 - Narrower
Concept UI M0281572
Preferred term GG 745
Entry term(s) 745, GG
GG-745
GG745
GI198745 - Narrower
Concept UI M0398765
Preferred term GI198745



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