| Descriptor English: | Endothelial Growth Factors | ||||||
| Descriptor Spanish: |
Factores de Crecimiento Endotelial
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| Descriptor Portuguese: | Fatores de Crescimento Endotelial | ||||||
| Descriptor French: | Facteurs de croissance endothéliale | ||||||
| Entry term(s): |
ECDGF Endo-GF Endothelial Cell Derived Growth Factors Endothelial Cell-Derived Growth Factors Endothelial Growth Factor Endothelial Growth Factor Polypeptides Growth Factor, Endothelial Growth Factor, alpha-Endothelial Growth Factor, beta-Endothelial Growth Factors, Endothelial alpha Endothelial Growth Factor alpha-Endothelial Growth Factor beta Endothelial Growth Factor beta-Endothelial Growth Factor |
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| Tree number(s): |
D12.644.276.390 D12.776.467.390 D23.529.390 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016228 | ||||||
| Scope note: | These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences. |
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| Annotation: | do not confuse with EGF; (EPIDERMAL GROWTH FACTOR) |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Growth Substances |
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| Previous Indexing: |
Fibroblast Growth Factor (1984-1990) Growth Substances (1966-1983) |
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| Public MeSH Note: | 91 |
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| History Note: | 91 |
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| Entry Version: | ECGF |
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| Related: |
Vascular Endothelial Growth Factor A
MeSH | ||||||
| DeCS ID: | 28920 | ||||||
| Unique ID: | D016228 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1990/05/30 | ||||||
| Revision Date: | 2006/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Endothelial Growth Factors
- Preferred
beta-Endothelial Growth Factor
- Narrower
alpha-Endothelial Growth Factor
- Narrower
| Concept UI |
M0024785 |
| Scope note | These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences. |
| Preferred term | Endothelial Growth Factors |
| Entry term(s) |
ECDGF Endo-GF Endothelial Cell Derived Growth Factors Endothelial Cell-Derived Growth Factors Endothelial Growth Factor Endothelial Growth Factor Polypeptides Growth Factor, Endothelial Growth Factors, Endothelial |
| Concept UI |
M0024784 |
| Preferred term | beta-Endothelial Growth Factor |
| Entry term(s) |
Growth Factor, beta-Endothelial beta Endothelial Growth Factor |
| Concept UI |
M0024783 |
| Preferred term | alpha-Endothelial Growth Factor |
| Entry term(s) |
Growth Factor, alpha-Endothelial alpha Endothelial Growth Factor |
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