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Descriptor English: Fertilins
Descriptor Spanish: Fertilinas
Descriptor fertilinas
Entry term(s) PH-30 alfa
PH-30 beta
fertilina
fertilina alfa
fertilina beta
proteína ADAM 1a
proteína ADAM 2
proteína ADAM1
proteína ADAM1a
proteína ADAM2
proteína PH-30
proteína de fusión PH 30
proteína de fusión PH-30
proteína fertilina
Scope note: Proteínas de superficie del esperma implicadas en la fusión del espermatozoide con el óvulo. Constan de dos subunidades, fertilina alfa (ADAM1) y beta (ADAM2), ambas pertenecientes a la familia de proteínas metaloproteasas-desintegrinas. La subunidad beta no tiene actividad catalítica.
Descriptor Portuguese: Fertilinas
Descriptor French: Fertilines
Entry term(s): ADAM 1a Protein
ADAM 2 Protein
ADAM1 Protein
ADAM1a Protein
ADAM2 Protein
Fertilin
Fertilin Protein
Fertilin alpha
Fertilin beta
PH 30 Fusion Protein
PH 30 Protein
PH 30 alpha
PH 30 beta
PH-30 Fusion Protein
PH-30 Protein
PH-30 alpha
PH-30 beta
alpha, Fertilin
alpha, PH-30
beta, Fertilin
beta, PH-30
Tree number(s): D08.811.277.656.675.374.102.750
D09.400.430.500.750
D12.776.395.033.750
D12.776.395.550.331
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072196
Scope note: Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.24.-
Public MeSH Note: 2017; FERTILINS was indexed under ADAM PROTEINS and MEMBRANE GLYCOPROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1992-2005
History Note: 2017 (1992)
DeCS ID: 56492
Unique ID: D000072196
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/27
Fertilins - Preferred
Concept UI M0199142
Scope note Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.
Preferred term Fertilins
Entry term(s) Fertilin
Fertilin Protein
PH 30 Fusion Protein
PH 30 Protein
PH-30 Fusion Protein
PH-30 Protein
Fertilin alpha - Narrower
Concept UI M0199136
Preferred term Fertilin alpha
Entry term(s) ADAM 1a Protein
ADAM1 Protein
ADAM1a Protein
PH 30 alpha
PH-30 alpha
alpha, Fertilin
alpha, PH-30
Fertilin beta - Narrower
Concept UI M0199137
Preferred term Fertilin beta
Entry term(s) ADAM 2 Protein
ADAM2 Protein
PH 30 beta
PH-30 beta
beta, Fertilin
beta, PH-30



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