| Descriptor English: | Furin | ||||||
| Descriptor Spanish: |
Furina
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| Descriptor Portuguese: | Furina | ||||||
| Descriptor French: | Furine | ||||||
| Entry term(s): |
Dibasic Processing Enzyme Furin Protein Paired Basic Amino Acid Cleaving Enzyme Processing Enzyme, Dibasic SPC1 Proteinase |
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| Tree number(s): |
D08.811.277.656.300.760.353 D08.811.277.656.837.249 D08.811.277.656.959.350.353 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D045683 | ||||||
| Scope note: | A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.4.21.75 | ||||||
| Previous Indexing: |
Serine Endopeptidases (1989-1992) Subtilisins (1993-2003) |
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| Public MeSH Note: | 2004; FURIN was indexed under SUBTILISINS 1993-2003 |
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| History Note: | 2004; use FURIN (NM) 1993-2003 |
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| DeCS ID: | 38168 | ||||||
| Unique ID: | D045683 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Furin
- Preferred
| Concept UI |
M0212390 |
| Scope note | A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids. |
| Preferred term | Furin |
| Entry term(s) |
Dibasic Processing Enzyme Furin Protein Paired Basic Amino Acid Cleaving Enzyme Processing Enzyme, Dibasic SPC1 Proteinase |
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