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Descriptor English: Lofepramine
Descriptor Spanish: Lofepramina
Descriptor lofepramina
Entry term(s) lopramina
Scope note: Derivado psicotrópico de la IMIPRAMINA que actúa como antidepresivo tricíclico y posee escasas propiedades anticolinérgicas. Es metabolizado a DESIPRAMINA.
Descriptor Portuguese: Lofepramina
Descriptor French: Lofépramine
Entry term(s): Deftan
Feprapax
Gamanil
Gamonil
Hydrochloride, Lofepramine
Leo 640
Lofepramine Hydrochloride
Lomont
Lopramine
Tree number(s): D03.633.300.240.520
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008127
Scope note: A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antidepressive Agents, Tricyclic
Registry Number: OCA4JT7PAW
CAS Type 1 Name: Ethanone, 1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)-
Previous Indexing: Dibenzazepines (1969-1978)
Public MeSH Note: 91; was see under DIBENZAZEPINES 1979-90
History Note: 91(79); was see under DIBENZAZEPINES 1979-90
DeCS ID: 8303
Unique ID: D008127
NLM Classification: QV 77.5
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1978/03/20
Revision Date: 2017/05/24
Lofepramine - Preferred
Concept UI M0012673
Scope note A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.
Preferred term Lofepramine
Entry term(s) Lopramine
Gamanil - Narrower
Concept UI M0354016
Preferred term Gamanil
Entry term(s) Deftan
Gamonil
Lofepramine Hydrochloride - Narrower
Concept UI M0330088
Preferred term Lofepramine Hydrochloride
Entry term(s) Hydrochloride, Lofepramine
Lomont - Narrower
Concept UI M0463979
Preferred term Lomont
Feprapax - Narrower
Concept UI M0463978
Preferred term Feprapax
Leo 640 - Narrower
Concept UI M0354015
Preferred term Leo 640



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