Search on: HAEM OXYGENASE 
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Descriptor English:   Heme Oxygenase (Decyclizing) 
Descriptor Spanish:   Hemo Oxigenasa (Desciclizante) 
Descriptor Portuguese:   Heme Oxigenase (Desciclizante) 
Synonyms English:   Heme Oxygenase
Oxygenase, Haem
Oxygenase, Heme
Haem Oxygenase  
Tree Number:   D08.811.682.690.708.410
Definition English:   A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt. 
History Note English:   98; was HEME OXYGENASE 1980-97 (see under HYDROXYLASES 1980-90) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   6568 
Unique Identifier:   D006419 

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