Search on: HELIX-TURN-HELIX MOTIFS 
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Descriptor English:   Helix-Turn-Helix Motifs 
Descriptor Spanish:   Secuencias Hélice-Giro-Hélice 
Descriptor Portuguese:   Sequências Hélice-Volta-Hélice 
Synonyms English:   Motifs, Helix-Turn-Helix
HTH Motif
Helix Turn Helix Motifs
Helix-Turn-Helix Motif
Motif, HTH
Motif, Helix-Turn-Helix
Motifs, HTH
Motifs, Helix Turn Helix
HTH Motifs  
Tree Number:   G02.111.570.820.709.275.500.360.360
Definition English:   The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9) 
Indexing Annotation English:   do not confuse with HELIX-LOOP-HELIX MOTIFS
History Note English:   96; was see HELIX-LOOP-HELIX MOTIFS 1994-95 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   32734 
Unique Identifier:   D019077 

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