Search on: HEMIDESMOSOMES 
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Descriptor English:   Hemidesmosomes 
Descriptor Spanish:   Hemidesmosomas 
Descriptor Portuguese:   Hemidesmossomos 
Synonyms English:   Hemidesmosome  
Tree Number:   A11.284.149.165.165.360
Definition English:   An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS. 
History Note English:   2001 
Allowable Qualifiers English:  
CH chemistry CL classification
DE drug effects EN enzymology
GE genetics IM immunology
ME metabolism MI microbiology
PS parasitology PA pathology
PH physiology RE radiation effects
SE secretion TR transplantation
UL ultrastructure VI virology
Record Number:   35266 
Unique Identifier:   D022002 

Occurrence in VHL:
 
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