Search on: HEPATOCYTE NUCLEAR FACTORS 
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Descriptor English:   Hepatocyte Nuclear Factors 
Descriptor Spanish:   Factores Nucleares del Hepatocito 
Descriptor Portuguese:   Fatores Nucleares de Hepatócito 
Tree Number:   D12.776.260.262
D12.776.660.352
D12.776.930.318
Definition English:   Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50995 
Unique Identifier:   D051536 

Occurrence in VHL:
 
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