Search on: HEPCIDINS 
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Descriptor English:   Hepcidins 
Descriptor Spanish:   Hepcidinas 
Descriptor Portuguese:   Hepcidinas 
Synonyms English:   Hepcidin
Liver-Expressed Antimicrobial Peptide
Pro-Hepcidin
Prohepcidin
Antimicrobial Peptide, Liver-Expressed
Liver Expressed Antimicrobial Peptide
Peptide, Liver-Expressed Antimicrobial
Pro Hepcidin  
Tree Number:   D12.776.494.249
D12.776.543.695.054.425
Definition English:   Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity. 
Pharmacological Action:   Anti-Infective Agents
 
See Related English:   Anemia
Hemochromatosis
 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   55332 
Unique Identifier:   D064451 

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