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Descriptor English:   Neuregulin-1 
Descriptor Spanish:   Neurregulina-1 
Descriptor Portuguese:   Neuregulina-1 
Synonyms English:   Differentiation Factor, neu
GGF Protein
Glial Growth Factor
NDF Protein
NRG1 Protein
Neuregulin 1
neu Differentiation Factor  
Tree Number:   D12.644.276.860.550.750
Definition English:   A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA. 
Indexing Annotation English:   do not confuse X ref GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR
History Note English:   2000; use NEUREGULIN-1 (NM) 1993-1999; for GLIAL GROWTH FACTOR use GLIA MATURATION FACTOR (NM) 1980-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34465 
Unique Identifier:   D020890 

Occurrence in VHL: