Search on: HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K 
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Descriptor English:   Heterogeneous-Nuclear Ribonucleoprotein K 
Descriptor Spanish:   Ribonucleoproteína Heterogénea-Nuclear Grupo K 
Descriptor Portuguese:   Ribonucleoproteínas Nucleares Heterogêneas Grupo K 
Synonyms English:   Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
dC-Stretch-Binding Protein
hnRNP K
hnRNP K Protein
Heterogeneous Nuclear Ribonucleoprotein K
Ribonucleoprotein K, Heterogeneous-Nuclear
dC Stretch Binding Protein  
Tree Number:   D12.776.157.725.813.750.500
D12.776.260.268
D12.776.664.962.813.750.500
Definition English:   A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties. 
Indexing Annotation English:   see SCR for specific hnRNP entries
History Note English:   2003; use HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K (NM) 1994-2002; for HNRNP K use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1994-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37415 
Unique Identifier:   D034641 

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