Search on: HETEROZYGOSITY, LOSS OF 
Descriptors Found: 1
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Descriptor English:   Loss of Heterozygosity 
Descriptor Spanish:   Pérdida de Heterocigocidad 
Descriptor Portuguese:   Perda de Heterozigosidade 
Synonyms English:   Allelic Loss
Allelic Losses
Heterozygosity Loss
Heterozygosity, Loss of  
Tree Number:   G05.365.590.029.530
Definition English:   The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted. 
Indexing Annotation English:   do not confuse entry term ALLELIC LOSS with ALLELIC IMBALANCE
See Related English:   Hemizygote
 
History Note English:   98 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   33610 
Unique Identifier:   D019656 

Occurrence in VHL:
 
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