| Descriptor English: | I-kappa B Kinase | ||||||
| Descriptor Spanish: |
Quinasa I-kappa B
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| Descriptor Portuguese: | Quinase I-kappa B | ||||||
| Descriptor French: | I-kappa B Kinase | ||||||
| Entry term(s): |
B Kinase, I-kappa CHUK Kinase Conserved Helix Loop Helix Ubiquitous Kinase Conserved Helix-Loop-Helix Ubiquitous Kinase Essential Modifier, NF-kappaB I Kappa B alpha Associated Protein Kinase I Kappa B alpha-Associated Protein Kinase I kappa B Kinase IKBKB IKK 1 Kinase IKK 2 Kinase IKK alpha IKK beta IKK epsilon IKK gamma IKKepsilon IkappaB Kinase IkappaB Kinase alpha IkappaB Kinase beta IkappaB Kinase epsilon IkappaB Kinase gamma IkappaBalpha Kinase Kinase alpha, IkappaB Kinase beta, IkappaB Kinase epsilon, IkappaB Kinase, I-kappa B Kinase, IkappaB NF kappaB Essential Modifier NF-kappaB Essential Modifier NK kappa B Activating Kinase NAK NK-kappa B-Activating Kinase NAK |
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| Tree number(s): |
D08.811.913.696.620.682.700.494 D12.776.476.563.494 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051550 | ||||||
| Scope note: | A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.10 | ||||||
| Public MeSH Note: | 2006; I-KAPPA B KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1997-2005 |
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| History Note: | 2006(1997) |
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| Related: |
I-kappa B Proteins
MeSH | ||||||
| DeCS ID: | 50718 | ||||||
| Unique ID: | D051550 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2017/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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I-kappa B Kinase
- Preferred
IkappaB Kinase gamma
- Narrower
IkappaB Kinase epsilon
- Narrower
IkappaB Kinase alpha
- Narrower
IkappaB Kinase beta
- Narrower
| Concept UI |
M0279189 |
| Scope note | A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit. |
| Preferred term | I-kappa B Kinase |
| Entry term(s) |
B Kinase, I-kappa I kappa B Kinase IkappaB Kinase Kinase, I-kappa B Kinase, IkappaB NK kappa B Activating Kinase NAK NK-kappa B-Activating Kinase NAK |
| Concept UI |
M0279184 |
| Preferred term | IkappaB Kinase gamma |
| Entry term(s) |
Essential Modifier, NF-kappaB IKK gamma NF kappaB Essential Modifier NF-kappaB Essential Modifier |
| Concept UI |
M0442052 |
| Preferred term | IkappaB Kinase epsilon |
| Entry term(s) |
IKK epsilon IKKepsilon Kinase epsilon, IkappaB |
| Concept UI |
M0279186 |
| Preferred term | IkappaB Kinase alpha |
| Entry term(s) |
CHUK Kinase Conserved Helix Loop Helix Ubiquitous Kinase Conserved Helix-Loop-Helix Ubiquitous Kinase I Kappa B alpha Associated Protein Kinase I Kappa B alpha-Associated Protein Kinase IKK 1 Kinase IKK alpha IkappaBalpha Kinase Kinase alpha, IkappaB |
| Concept UI |
M0279183 |
| Preferred term | IkappaB Kinase beta |
| Entry term(s) |
IKBKB IKK 2 Kinase IKK beta Kinase beta, IkappaB |
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