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Descriptor English: Erythromycin Estolate
Descriptor Spanish: Estolato de Eritromicina
Descriptor estolato de eritromicina
Entry term(s) dodecil sulfato propionato de eritromicina
lauril sulfato propionato de eritromicina
Scope note: Antibiótico macrólido producido por Streptomyces arythreus. Es la sal lauril sulfato del éster propiónico de la eritromicina. Esta sal de eritromicina actúa principalmente como agente bacteriostático. En los organismos sensibles inhibe la síntesis de proteínas al unirse a las subunidades ribosómicas 50S. Este proceso de unión inhibe la actividad peptidil trransferasa e interfiere en la translocación de los aminoácidos durante la traducción y ensamblaje de las proteínas.
Descriptor Portuguese: Estolato de Eritromicina
Descriptor French: Érythromycine estolate
Entry term(s): Eromycin
Erythromycin Propionate Dodecyl Sulfate
Erythromycin Propionate Lauryl Sulfate
Erythromycin Propionate Monododecyl Sulfate
Estolate, Erythromycin
Ilosone
Lauromicina
Tree number(s): D02.540.576.500.992.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004918
Scope note: A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Enzyme Inhibitors
Gastrointestinal Agents
Protein Synthesis Inhibitors
Registry Number: XRJ2P631HP
CAS Type 1 Name: Erythromycin, 2'-propanoate, dodecyl sulfate (salt)
Previous Indexing: Erythromycin (1970-1974)
Propionates (1974)
Sodium Dodecyl Sulfate (1974)
Public MeSH Note: 91; was see under ERYTHROMYCIN 1975-90
History Note: 91(75); was see under ERYTHROMYCIN 1975-90
DeCS ID: 28028
Unique ID: D004918
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2015/06/22
Erythromycin Estolate - Preferred
Concept UI M0007723
Scope note A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Preferred term Erythromycin Estolate
Entry term(s) Erythromycin Propionate Dodecyl Sulfate
Erythromycin Propionate Lauryl Sulfate
Erythromycin Propionate Monododecyl Sulfate
Estolate, Erythromycin
Ilosone - Narrower
Concept UI M0352018
Preferred term Ilosone
Lauromicina - Narrower
Concept UI M0352017
Preferred term Lauromicina
Eromycin - Narrower
Concept UI M0352019
Preferred term Eromycin



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