DeCS

Descriptor English:

Karyopherins

Descriptor Spanish:

Carioferinas

Spanish from Spain

Descriptor	carioferinas
Entry term(s)	carioferina exportina importinas
Scope note:	Familia de proteínas implicadas en el TRANSPORTE NUCLEOCITOPLASMÁTICO. Las carioferinas son moléculas heteroméricas constituidas por dos tipos principales de compuestos, las CARIOFERINAS ALFA y las CARIOFERINAS BETA, que funcionan juntas para transportar moléculas a través de PROTEÍNAS DEL COMPLEJO DE POROS NUCLEAR. Algunas otras proteínas, como la PROTEÍNA DE UNIÓN AL GTP RAN y la PROTEÍNA DE SUSCEPTIBILIDAD A LA APOPTOSIS CELULAR, se unen a las carioferinas y participan en el proceso de transporte.

Descriptor Portuguese:

Carioferinas

Descriptor French:

Caryophérines

Entry term(s):

Exportin
Exportins
Importin
Importins
Karyopherin
Transportin
Transportins

Tree number(s):

D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D028884

Scope note:

A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Previous Indexing:

Nuclear Proteins (1995-2001)
Receptors, Cytoplasmic and Nuclear (1995-2001)

Public MeSH Note:

2002; IMPORTIN (now KARYOPHERINS) was indexed under NUCLEAR PROTEINS 1995-2001; TRANSPORTIN (now KARYOPHERINS) was indexed under NUCLEAR PROTEINS & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1995-2001

Concept UI	M0383377
Scope note	A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
Preferred term	Karyopherins
Entry term(s)	Karyopherin Transportin Transportins

Concept UI	M0383378
Scope note	A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
Preferred term	Exportins
Entry term(s)	Exportin

Concept UI	M0240471
Scope note	A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
Preferred term	Importins
Entry term(s)	Importin

We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.