| Descriptor English: | Kallikreins | ||||||
| Descriptor Spanish: |
Calicreínas
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| Descriptor Portuguese: | Calicreínas | ||||||
| Descriptor French: | Kallicréines | ||||||
| Entry term(s): |
Callicrein Dilminal Enzyme, Kinin-Forming Kallidinogenase Kalliginogenase Kallikrein Kallikrein A Kallikrein B' Kallikrein Light Chain Kinin Forming Enzyme Kinin-Forming Enzyme Kininogenase Light Chain, Kallikrein Padutin alpha Kallikrein alpha-Kallikrein beta Kallikrein beta Kallikrein B beta-Kallikrein beta-Kallikrein B |
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| Tree number(s): |
D08.811.277.656.300.760.442 D08.811.277.656.959.350.442 D12.776.124.125.597 D23.119.597 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007610 | ||||||
| Scope note: | Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77). |
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| Annotation: | /antag permitted but consider KALLIKREIN-TRYPSIN INACTIVATOR |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Coagulants Fertility Agents, Male |
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| Registry Number: | EC 3.4.21.- | ||||||
| Public MeSH Note: | 2000; see KALLIKREIN 1963-1999 |
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| History Note: | 2000(1963) |
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| Related: |
Coagulants
MeSH | ||||||
| DeCS ID: | 23326 | ||||||
| Unique ID: | D007610 | ||||||
| NLM Classification: | QU 136 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2000/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2009/07/06 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Kallikreins
- Preferred
Kallikrein Light Chain
- Narrower
Padutin
- Narrower
Kallikrein A
- Narrower
beta-Kallikrein
- Narrower
beta-Kallikrein B
- Narrower
Dilminal
- Narrower
Kallikrein B'
- Narrower
alpha-Kallikrein
- Narrower
| Concept UI |
M0011897 |
| Scope note | Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77). |
| Preferred term | Kallikreins |
| Entry term(s) |
Callicrein Enzyme, Kinin-Forming Kallidinogenase Kalliginogenase Kallikrein Kinin Forming Enzyme Kinin-Forming Enzyme Kininogenase |
| Concept UI |
M0011902 |
| Preferred term | Kallikrein Light Chain |
| Entry term(s) |
Light Chain, Kallikrein |
| Concept UI |
M0332548 |
| Preferred term | Padutin |
| Concept UI |
M0011898 |
| Preferred term | Kallikrein A |
| Concept UI |
M0011895 |
| Preferred term | beta-Kallikrein |
| Entry term(s) |
beta Kallikrein |
| Concept UI |
M0011896 |
| Preferred term | beta-Kallikrein B |
| Entry term(s) |
beta Kallikrein B |
| Concept UI |
M0332549 |
| Preferred term | Dilminal |
| Concept UI |
M0011899 |
| Preferred term | Kallikrein B' |
| Concept UI |
M0011894 |
| Preferred term | alpha-Kallikrein |
| Entry term(s) |
alpha Kallikrein |
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