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Descriptor English: Mazindol
Descriptor Spanish: Mazindol
Descriptor mazindol
Scope note: Agente anorexígeno tricíclico, no relacionado con la ANFETAMINA y menos tóxico, pero con efectos secundarios similares. Inhibe la recaptación de catecolaminas y bloquea la unión de la cocaína al transportador de captación de dopamina.
Descriptor Portuguese: Mazindol
Descriptor French: Mazindol
Entry term(s): AN-448
AN448
Diestet
Mazanor
Mazindole
Sanjorex
Sanorex
Solucaps
Teronac
Teronak
Tree number(s): D03.633.100.513.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008454
Scope note: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Central Nervous System Stimulants
Adrenergic Uptake Inhibitors
Dopamine Uptake Inhibitors
Registry Number: C56709M5NH
CAS Type 1 Name: 3H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
Previous Indexing: Imidazoles (1972-1974)
Indoles (1972-1974)
Public MeSH Note: 91; was see under INDOLES 1975-90
History Note: 91(75); was see under INDOLES 1975-90
DeCS ID: 8622
Unique ID: D008454
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2017/05/24
Mazindol - Preferred
Concept UI M0013149
Scope note Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Preferred term Mazindol
Entry term(s) Mazindole
Diestet - Narrower
Concept UI M0473860
Preferred term Diestet
Mazanor - Narrower
Concept UI M0353735
Preferred term Mazanor
Solucaps - Narrower
Concept UI M0473861
Preferred term Solucaps
Teronac - Narrower
Concept UI M0353740
Preferred term Teronac
Entry term(s) Teronak
AN-448 - Narrower
Concept UI M0353736
Preferred term AN-448
Entry term(s) AN448
Sanorex - Narrower
Concept UI M0353738
Preferred term Sanorex
Entry term(s) Sanjorex



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