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Descriptor English: Muzolimine
Descriptor Spanish: Muzolimina
Descriptor muzolimina
Scope note: Diurético pirazólico de acción prolongada y alta capacidad de acción. Fue propuesto para la insificiencia renal y la hipertensión pero más tarde se retiró, a nivel mundial, debido a sus graves efectos neurológicos.
Descriptor Portuguese: Muzolimina
Descriptor French: Muzolimine
Entry term(s): Bay G 2821
G 2821, Bay
Tree number(s): D03.383.129.539.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009156
Scope note: A pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Diuretics
Registry Number: 07Z36289ZX
CAS Type 1 Name: 3H-Pyrazol-3-one, 5-amino-2-(1-(3,4-dichlorophenyl)ethyl)-2,4-dihydro-
Previous Indexing: Pyrazoles (1966-1979)
Public MeSH Note: 91; was see under PYRAZOLES 1980-90
History Note: 91(80); was see under PYRAZOLES 1980-90
DeCS ID: 9348
Unique ID: D009156
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1979/05/30
Revision Date: 2016/07/01
Muzolimine - Preferred
Concept UI M0014278
Scope note A pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.
Preferred term Muzolimine
Bay G 2821 - Narrower
Concept UI M0373557
Preferred term Bay G 2821
Entry term(s) G 2821, Bay



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