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Descriptor English: Synaptic Transmission
Descriptor Spanish: Transmisión Sináptica
Descriptor transmisión sináptica
Entry term(s) neurotransmisión
transmisión neuronal
Scope note: Comunicación desde una NEURONA hasta un objetivo (neurona, músculo o célula secretora) a través de una SINAPSIS. En la transmisión sináptica química, la neurona presináptica libera un NEUROTRANSMISOR que se difunde a lo largo del espacio sináptico y se une a receptores sinápticos específicos, activándolos. Dichos receptores activados modulan los canales iónicos específicos y/o los sistemas de segundo mensajero en la célula postsináptica. En la transmisión sináptica eléctrica, las señales eléctricas se comunican en forma de flujo de corriente iónica a través de la SINAPSIS ELÉCTRICA.
Descriptor Portuguese: Transmissão Sináptica
Descriptor French: Transmission synaptique
Entry term(s): Neural Transmission
Neurotransmission
Transmission, Neural
Transmission, Synaptic
Tree number(s): G02.111.820.850
G04.835.850
G07.265.880
G11.561.830
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009435
Scope note: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Annotation: differentiate entry term NEURAL TRANSMISSION from NEURAL CONDUCTION; consider also NEURAL INHIBITION; neuromuscular transmission = NEUROMUSCULAR JUNCTION / physiol + SYNAPTIC TRANSMISSION
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Neural Conduction (1966-1967)
Public MeSH Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION
Online Note: use SYNAPTIC TRANSMISSION to search NEURAL TRANSMISSION 1969-93, NEUROHUMORAL TRANSMISSION 1968, & NERVE TRANSMISSION 1968-93
History Note: 94; was NEURAL TRANSMISSION 1969-93, was NEUROHUMORAL TRANSMISSION 1968; NERVE TRANSMISSION was see NEURAL TRANSMISSION 1969-93
Entry Version: SYNAPTIC TRANSM
Related: Gap Junctions MeSH
Synapses MeSH
DeCS ID: 31881
Unique ID: D009435
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/23
Synaptic Transmission - Preferred
Concept UI M0014683
Scope note The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Preferred term Synaptic Transmission
Entry term(s) Neural Transmission
Neurotransmission
Transmission, Neural
Transmission, Synaptic



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