Search on: ONCOGENE PROTEINS V-ERBB 
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Descriptor English:   Oncogene Proteins v-erbB 
Descriptor Spanish:   Proteínas Oncogénicas v-erbB 
Descriptor Portuguese:   Proteínas Oncogênicas v-erbB 
Synonyms English:   Oncogene Products v-erbB
Oncogene Proteins erbB
Oncogene Products v erbB
Oncogene Proteins v erbB
v erbB Proteins
erbB Oncogene Proteins
v-erbB Proteins  
Tree Number:   D12.776.624.664.520.750.883
D12.776.964.700.750.883
D12.776.964.775.750.883
Definition English:   Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) whose kinase domain is constitutively activated by deletion of the ligand-binding domain. 
Indexing Annotation English:   IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short X ref
History Note English:   95; was ONCOGENE PROTEINS ERBB (NM) 1987-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32105 
Unique Identifier:   D018739 

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