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Descriptor English: Ouabain
Descriptor Spanish: Ouabaína
Descriptor ouabaína
Entry term(s) G-estrofantina
acocanterina
Scope note: Glicósido cardioactivo compuesto de ramnosa y ouabagenina que se obtiene de semillas de Strophantus gratus y de otras plantas de la familia Apocynaceae. Se usa como la DIGITAL. Se emplea comúnmente en estudios de biología celular como inhibidor de la ATPASA INTERCAMBIADORA DE NA(+)-K(+).
Descriptor Portuguese: Ouabaína
Descriptor French: Ouabaïne
Entry term(s): Acocantherin
Acolongifloroside K
G Strophanthin
G-Strophanthin
Tree number(s): D04.210.500.155.580.130.750.600
D09.408.180.810.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010042
Scope note: A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Cardiotonic Agents
Enzyme Inhibitors
Registry Number: 5ACL011P69
CAS Type 1 Name: Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1,5,11,14,19-pentahydroxy-, (1beta,3beta,5beta,11alpha)-
Public MeSH Note: 65; was see under STROPHANTHIN (now STROPHANTHINS) 1963-64
History Note: 65(63); was see under STROPHANTHIN (now STROPHANTHINS) 1963-64
DeCS ID: 10220
Unique ID: D010042
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Ouabain - Preferred
Concept UI M0015582
Scope note A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
Preferred term Ouabain
Entry term(s) Acocantherin
Acolongifloroside K
G Strophanthin
G-Strophanthin



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