Search
Descriptor English: Pentoxifylline
Descriptor Spanish: Pentoxifilina
Descriptor pentoxifilina
Scope note: Derivado de la METILXANTINA que inhibe la fosfodiesterasa y afecta la reología de la sangre. Mejora el flujo sanguíneo al incrementar la flexibilidad de los eritrocitos y los leucocitos. Inhibe también la agregación plaquetaria. La pentoxifilina modula la actividad inmunológica estimulando la producción de citoquinas.
Descriptor Portuguese: Pentoxifilina
Descriptor French: Pentoxifylline
Entry term(s): Agapurin
BL 191
BL-191
BL191
Oxpentifylline
Pentoxil
Torental
Trental
Tree number(s): D03.633.100.759.758.824.651.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010431
Scope note: A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Phosphodiesterase Inhibitors
Platelet Aggregation Inhibitors
Radiation-Protective Agents
Vasodilator Agents
Free Radical Scavengers
Registry Number: SD6QCT3TSU
CAS Type 1 Name: 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
Previous Indexing: Xanthines (1972-1976)
Public MeSH Note: 91; see THEOBROMINE 1977-90
History Note: 91(77)
DeCS ID: 10625
Unique ID: D010431
NLM Classification: QV 107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/16
Revision Date: 2016/05/31
Pentoxifylline - Preferred
Concept UI M0016198
Scope note A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
Preferred term Pentoxifylline
Entry term(s) Oxpentifylline
Trental - Narrower
Concept UI M0016199
Preferred term Trental
Pentoxil - Narrower
Concept UI M0534524
Preferred term Pentoxil
Torental - Narrower
Concept UI M0016201
Preferred term Torental
Agapurin - Narrower
Concept UI M0016200
Preferred term Agapurin
BL-191 - Narrower
Concept UI M0353118
Preferred term BL-191
Entry term(s) BL 191
BL191



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey