Search on: RECEPTOR, ERBB-2 
Descriptors Found: 1
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Descriptor English:   Receptor, ErbB-2 
Descriptor Spanish:   Receptor ErbB-2 
Descriptor Portuguese:   Receptor ErbB-2 
Synonyms English:   Antigens, CD340
CD340 Antigen
Metastatic Lymph Node Gene 19 Protein
Neu Receptor
Oncogene Protein HER-2
Proto-Oncogene Proteins c-erbB-2
Proto-oncogene Protein Neu
Proto-oncogene c-ErbB-2
Receptor, Neu
Receptors, erbB-2
Tyrosine Kinase-type Cell Surface Receptor HER2
p185(c-neu)
p185erbB2 Protein
CD340 Antigens
ErbB-2 Receptor
HER 2 Proto Oncogene Protein
Neu, Proto-oncogene Protein
Oncogene Protein HER 2
Proto Oncogene Protein HER 2
Proto Oncogene Proteins c erbB 2
Proto-Oncogene Protein, HER-2
Proto-Oncogene Protein, erbB-2
Proto-Oncogene Protein, neu
Tyrosine Kinase type Cell Surface Receptor HER2
c erbB 2 Protein
c-ErbB-2, Proto-oncogene
erbB 2 Proto Oncogene Protein
erbB 2 Receptor Protein Tyrosine Kinase
erbB-2 Receptors
neu Proto Oncogene Protein
c-erbB-2 Protein
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
neu Proto-Oncogene Protein
HER-2 Proto-Oncogene Protein
Proto-Oncogene Protein p185(neu)
Proto-Oncogene Protein HER-2  
Tree Number:   D08.811.913.696.620.682.725.400.009.400
D12.776.543.750.630.009.400
D12.776.543.750.750.400.074.400
D12.776.624.664.700.642
D23.050.301.500.600.700
D23.050.705.552.600.550
D23.101.140.642
Definition English:   A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member. 
See Related English:   Genes, erbB-2
Trastuzumab
 
History Note English:   2000 (1995) 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   32062 
Unique Identifier:   D018719 

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