| Descriptor English: | Retinaldehyde | ||||||
| Descriptor Spanish: |
Retinaldehído
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| Descriptor Portuguese: | Retinaldeído | ||||||
| Descriptor French: | Rétinal | ||||||
| Entry term(s): |
11 cis Retinal 11-cis-Retinal 11-trans-Retinal 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal Aldehyde, Vitamin A Axerophthal Retinal Retinene Retinyl Aldehydde Vitamin A Aldehyde all-trans-Retinal |
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| Tree number(s): |
D02.047.850 D02.455.326.271.665.202.495.690 D02.455.426.392.368.367.379.249.700.690 D02.455.849.131.495.690 D02.455.849.291.605 D23.767.261.700.690 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D012172 | ||||||
| Scope note: | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
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| Annotation: | /biosyn /physiol permitted |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Registry Number: | RR725D715M | ||||||
| CAS Type 1 Name: | Retinal | ||||||
| Public MeSH Note: | 91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83 |
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| Online Note: | search VITAMIN A 1968-74 |
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| History Note: | 91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83 |
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| DeCS ID: | 12588 | ||||||
| Unique ID: | D012172 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/06/09 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Retinaldehyde
- Preferred
11-cis-Retinal
- Narrower
11-trans-Retinal
- Narrower
| Concept UI |
M0018957 |
| Scope note | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
| Preferred term | Retinaldehyde |
| Entry term(s) |
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal Aldehyde, Vitamin A Axerophthal Retinal Retinene Retinyl Aldehydde Vitamin A Aldehyde |
| Concept UI |
M0018958 |
| Scope note | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
| Scope note | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
| Preferred term | 11-cis-Retinal |
| Entry term(s) |
11 cis Retinal |
| Concept UI |
M000743797 |
| Preferred term | 11-trans-Retinal |
| Entry term(s) |
all-trans-Retinal |
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